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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク History of research on Caenorhabditis elegans ： ウィキペディア英語版 History of research on Caenorhabditis elegans The nematode worm ''Caenorhabditis elegans'' was first studied in the laboratory by Victor Nigon and Ellsworth Dougherty in the 1940s, but came to prominence after being adopted by Sydney Brenner in 1963 as a model organism for the study of developmental biology using genetics. In 1974, Brenner published the results of his first genetic screen, which isolated hundreds of mutants with morphological phenotypes. In the 1980s, John Sulston and co-workers identified the lineage of all 959 cells in the adult hermaphrodite, the first genes were cloned, and the physical map began to be constructed. In 1998, the worm became the first multi-cellular organism to have its genome sequenced. Notable research using ''C. elegans'' includes the discoveries of caspases, RNA interference, and microRNAs. Six scientists have won the Nobel prize for their work on ''C. elegans''. == Early research == ''C. elegans'' was first described in 1900 by Émile Maupas, who isolated it from soil in Algeria. Ellsworth Dougherty proposed in 1948 that free-living nematodes of the sub-order Rhabditina might be useful for genetic study, noting their relative structural simplicity and invariant cell lineage (eutely). Dougherty and Victor Nigon obtained the first mutant, from a laboratory culture of the closely related nematode ''Caenorhabditis briggsae''. However much of the early laboratory work on ''Caenorhabditis'' nematodes was directed towards the establishment of a defined axenic culture medium. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「History of research on Caenorhabditis elegans」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.